The article discusses why depression hurts. It says that affective neuroscience consists of seven primary functions namely seeking, rage, fear, sexual lust, maternal care, separation distress or panic, and play. It states that depression is closely related to sustained overactivity of the panic system resulting to psychological despair if prolonged, and to the despair phase after acute panic response. It adds that depression reflects the behavioral agitation of panic in terms of animal modeling.
Why does depression hurt? ancestral primary-process separation-distress (PANIC/GRIEF) and diminished brain reward (SEEKING) processes in the genesis of depressive affect
