Rats selectively bred for low levels of play-induced 50kHz vocalizations as a model for Autism Spectrum Disorders
J. Burgdorf, J.R. Moskal, S.M. Brudzynski, J. Panksepp
· 2013
★ NIFPlay Rating: 9
Rating Scale
10 Rigorous play-specific science
6–9 General biological science
5 Sound play research (uncontrolled)
1–4 Less rigorous / indirect
0 Indirect but high value
Develops a rat model for autism by selectively breeding for reduced play vocalizations, demonstrating social play deficits and testing NMDA receptor-targeted treatments.
